Designing Clinical Research

Selected as a Doody's Core Title for 2022 and 2023! For more than 30 years, Designing Clinical Research has set .

• Questions and Answers

Selected as a Doody's Core Title for 2022 and 2023!

• Covers clinical research in its many forms, including clinical trials, observational studies, translational science, and patient-oriented research.
• Presents epidemiologic terms and principles and advanced conceptual material in a practical and reader-friendly manner.
• Discusses key changes in the field, including confounding and directed acyclic graphs, surrogate outcomes and biomarkers, instrumental variables and Mendelian randomization, regression discontinuity designs, alternative data sources, AI and machine learning, pilot studies, as well as an update on P values and Bayesian analysis..
• Covers modifications of classic randomized trials, such as pre/post, interrupted time series, difference-in-differences, stepped wedge and cluster randomized designs, as well as randomized trials in health systems.
• Adds new chapters on qualitative approaches to clinical research and on community-engaged research
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Chief Executive Officer, California Pacific Medical Center; Adjunct Professor, Department of Epidemiology & Biostatistics, University of California, San Francisco

Professor of Epidemiology & Biostatistics, and of Pediatrics; Chief, Division of Clinical Epidemiology; Attending Physician, Department of Pediatrics, University of California, San Francisco

Founding Director, San Francisco Coordinating Center; Senior Scientist, California Pacific Medical Center Research Institute; Professor Emeritus, University of California, San Francisco

Professor of Medicine, Associate Dean for Clinical and Translational Research, University of California, San Francisco